For the second time in the space of three weeks Michael Bisping has been defeated in at UFC main event and, once again, it was a left hand strike which led to his undoing.

Kelvin Gastelum scored the biggest win of his professional career at UFC Shanghai on Saturday, dropping the former middleweight champion midway through the first round with a stunning two punch combination and finishing the fight moments later with ground strikes.

Bisping, who took the fight on short notice after Anderson Silva withdrew due to a potential USADA violation, was looking to erase the memories of his failed title defense inside Madison Square Garden earlier this month. However, the Brit was unable to get going as Gastelum, the faster of the two fighters, used his footwork to present a mobile target to his opponent. Bisping did have some success with a handful of strikes early but, just before the halfway mark of the first round, it was Gastelum who landed the telling blow which led the bout to its conclusion.

Slipping a Bisping right hook, Gastelum pawed out with a right of his own and followed immediately with a left hook to the chin which sent Bisping to the canvas. Gastelum followed up with a handful of strikes on the ground before referee Marc Goddard called a halt to the bout.

Woah.

Huuuuuuuge left hand from Kelvin Gastelum! 😱

Michael Bisping is finished for the second time in three weeks #UFCShanghai pic.twitter.com/jLyoChFT9F

— UFC on BT Sport (@btsportufc) November 25, 2017

Bisping falls to 31-8 in his professional career and will likely retire from the sport following a final UFC appearance in London in the first quarter of next year.

Gastelum, meanwhile, improves to 15-3 (1 NC) with the biggest win of his career in the middleweight division.